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Klinefelter syndrome or Klinefelter's syndrome (KS) (/ˈklaɪnfɛltər/) also known as 47,XXY or XXY, is the set of symptoms that result from two or more X chromosome in males. The primary feature is sterility. Often symptoms may be subtle and many people do not realize they are affected. Sometimes symptoms are more prominent and may include weaker muscles, greater height, poor coordination, less body hair, smaller genitals, breast growth, and less interest in sex. Often it is only at puberty that these symptoms are noticed.

Vala Mal Doran thought Dr. Hutchison had Klinefelder's Syndrome. (SG1: "Morpheus")

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