Jodelle Ferland was born in Nanaimo, British Columbia, daughter of Valerie Ferland. Jodelle is of French, British and Austrian heritage. She made her movie debut at age 4 in the TV-movie Mermaid, for which she received a Daytime Emmy Award nomination, making her the youngest nominee in Emmy history. She has since made guest appearances in several television series, including Smallville, Dark Angel, Stargate SG-1, Stargate: Atlantis, and Supernatural.
Ferland is a friend of actor Cameron Bright.
In 2005, she starred in the Terry Gilliam drama Tideland, for which she received a Genie Award nomination in the Best Actress category.
Later, she appeared in the 2006 film Silent Hill, an adaptation of the well-known video game. In 2010 she played Bree a vampire in Twilight saga:Eclipse.
Ferland used to star in the Canadian series, Dark Matter, playing the engineer, Das/Five alongside David Hewlett (Meredith Rodney McKay) who plays the team's handler, Tabor Calchek.