Hoffan drug

The Hoffan Drug was a compound created by the Hoffan people in the Pegasus galaxy.

The drug was created by the scientists of Hoff over many generations due to the constant Cullings by the Wraith. Working on their predessors knowledge, newer generations of scientists would use their research in creating a compound that would make their race immune to the Wraith's ability to feed on them. They were able to perfect the compound through the aid of the Atlantis Expedition's Doctor, Carson Beckett. It was tested on a terminally ill Hoffan who was left in a room wih a captured Wraith who attempted to feed on him but broke away from the action. After this, Steve's internal organs shut down as e was poisoned by the drug and died. The volunteer also died as a result. Seeing this as a success, the drug was administered to the Hoffan population, however, the Atlantis Expedition realized that the drug had a 50% mortality rate resulting in many who were innoculated dying. 

The Wraith would eventually learn of the Hoffan Drug and exterminate the Hoffan race for the threat it represented leaving Hoff in ruins. From the ancient vaults where the Hoffan scientists kept their research, Michael Kenmore came and looted the area of data relating to the compound. Using a clone of Carson Beckett, Michael perfected the drug and began to subtely distribute it to various Human worlds in the Pegasus galaxy as part of an opening volley in his personal war against the Wraith. Many Wraith Hive's that engaged in cullings found themselves poisoned and dying after feeding on these Humans. In addition to this, the Human worlds began to suffer from a plague of deaths caused by the drugs mortality rate which resulted in 30% of those administered by the drug dying in the process. It was believed that Michael's forces distributed the drug through food or water on various worlds in his hopes of oollectively weakening the Wraith by targeting their food sources.